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filingDate 2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b31bff0930504d7d71e145f09e1f0fb8
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publicationDate 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013040175-A
titleOfInvention Solid composition for the treatment of midnight insomnia and method of treatment thereof
abstract A pharmaceutical composition for treating midnight insomnia (MOTN) and methods of using the composition are provided. A solid pharmaceutical composition comprising zolpitem or a salt thereof that is a hypnotic sedative, and treatment of a subject who is awake from sleep, difficult to return to sleep and wants to wake up and resume sleep for less than 5 hours How to use. The composition is suitable for administration of a solid pharmaceutical composition comprising an amount of zolpidem or a salt thereof that induces effective sleep of less than 1.30 × 10 −5 moles, and the administration step of the composition is intended for the subject to sleep The composition provides delivery of zolpidem through the subject's oral mucosa, dissolves or disintegrates within 10 minutes in the subject's mouth, and the amount is 4 after administration without residual sedation. It is preferable that the usage is the amount that the subject wakes up in time. The composition is a lozenge or tablet and is preferably administered sublingually. [Selection figure] None
priorityDate 2005-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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