| abstract |
A method for treating conditions such as autoimmune diseases, degenerative diseases, and graft-versus-host disease is provided. A medicament for the treatment of a disease characterized by the production of effector T cells, comprising an agent that inhibits the production of effector T cells and restricts the function and / or activity of the cells. The treatment includes analyzing the periodic changes in the immune system by monitoring the patient and exposing the patient to an agent that treats the disease. The disease is an autoimmune disease or transplant rejection; the agent is selected from the group consisting of an antiproliferative agent, an antimetabolite, irradiation, dsRNA and an antibody; the agent is such that effector T cell expansion does not occur And / or is administered when or just before the effector T cells begin to clonal expansion, such that the number of effector T cells decreases or disappears. [Selection figure] None |