| abstract |
Disclosed is a drug for inhibiting and treating TLR9 and preventing and treating autoimmune diseases, inflammation, allergies, asthma, graft rejection or graft-versus-host disease. A TLR9 inhibitor comprising a compound represented by the following general formula (1) as an active ingredient. [Wherein, R 1 , R 2 and R 3 may be the same or different from each other, and are a hydrogen atom, a halogen atom, a C 1-4 alkyl group, a C 1-4 alkyloxy group, or a C 6-10 aryloxy. A group or a C 10-14 aralkyloxy group, R 4 , R 5 , R 6 , R 7 may be the same or different from each other, represent a C 1-4 alkyl group, and l, m, n are They may be the same or different from each other and represent an integer of 0 to 4. ] [Selection figure] None |