http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013031626-A

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filingDate 2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_944474f7ae6f518f21910a99acacda53
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publicationDate 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2013031626-A
titleOfInvention Drug substance aseptic purification equipment
abstract Disclosed is an apparatus for sterilizing and purifying a drug substance capable of further reducing the content of impurities. A crude drug substance is dissolved in a first solvent to prepare a crude drug substance solution, then sterilized in a first step, a sterile filtered second solvent is added, and the drug substance is crystallized. In the sterilization / purification apparatus for active pharmaceutical ingredients for performing the third process of filtering, drying and filtering, drying, and filling the resulting powdery active pharmaceutical ingredient into a container, each process is a series of steps. In order to carry out in the inert gas atmosphere by the in-line system, the drug substance connected by piping from the crude drug substance inlet to the container filling device 39, filtered and dried in the third step, is downstream from the filter dryer. It is carried out from the carry-out port by an inert gas stream, and is conveyed by the vibration feeder 29 to the powder transfer hopper 31 located below the filter dryer, and is conveyed to the pulverizer 36 by the screw conveyor. [Selection] Figure 2
priorityDate 2011-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 23.