http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013013405-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8def5adebe7616f8937efbbba81e4ce6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25afcb7bf2c0d839bb9118680e60e1ae |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2012-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72607bc075feb749d7f462d1bcb62d23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2be9ee96a1eb372a1bf3c7f9de75d2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25ea1da962794d77068ce9994bedf68b |
| publicationDate | 2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2013013405-A |
| titleOfInvention | Morocco cell line, production method and use thereof |
| abstract | To provide a somatic cell line of Morocco, particularly a somatic cell line derived from the gonad of Honmoroko, particularly a cell line capable of supporting functional sperm or oogenesis and a method for producing the same. To provide an evaluation system for the influence of chemical substances on fish and other animals using the cell line as a biosensor. The present invention stably maintains the properties of (a) no decrease in growth rate, (b) expressing Sox9a and WT1a, and (c) expressing androgen receptor and estrogen receptor-1. A somatic cell line derived from moroko gonads. Furthermore, (d) a cell line that stably retains the property of expressing Foxl2. A method for culturing fish germ cells, comprising culturing cells or fertilized eggs collected from fish gonads using the cells as supporting cells. An androgen-like or anti-androgenic action and / or an estrogen-like or anti-estrogen of a test substance, characterized in that a test substance is brought into contact with cells of the cell line and the expression variation of an androgen and / or estrogen response gene is measured. Evaluation method of action. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016171797-A |
| priorityDate | 2011-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 348.