| abstract |
The present invention includes, for example, psoriasis, atopic dermatitis, Rosacare, lupus, multiple sclerosis, rheumatoid arthritis, type I diabetes, asthma, cancer, autoimmune thyroid disease, ulcerative colitis, Crohn's disease, Alzheimer's disease, To prevent, treat or alleviate diseases and complications, including leukemia, eye diseases such as diabetic retinopathy and macular degeneration and other autoimmune diseases and conditions where immunosuppression is desirable, for example, in organ transplantation As JAK kinases and protein tyrosine kinase inhibitors, the general formula I used for treatment-alone or in combination with one or more other pharmaceutically active compounds: [Wherein, A, R 1 , R 2 , R 3 , R 4 , R 5 , R 9 , m, and n are as defined in this specification.] Or a pharmaceutically acceptable salt, hydrate, or solvate thereof. |