| abstract |
Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using compounds that modulate PKM2 in the treatment of cancer. Compositions and pharmaceutical kits comprising the compounds of the invention and related to pyruvate kinase function (eg, PKM2 function), including, for example, cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia (BPH) The use of such compositions and kits in methods of treating diseases and conditions are provided. |