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publicationDate 2012-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2012531198-A
titleOfInvention Bacterial expression of artificial genes for production of CRM197 and its derivatives
abstract The present invention relates to a polynucleotide sequence comprising SEQ ID NO: 1 which encodes CRM197 and is optimized for its expression in E. coli. As a result, the present invention relates to a method for producing CRM197 in E. coli via the fusion protein CRM197-tag.
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