| abstract |
The present invention is for the treatment of disorders mediated by α-carbonic anhydrase isoforms selected from hypertension (glaucoma), epilepsy, Lennox-Gastaut syndrome, altitude sickness, headache, neuropathy and obesity. 4- (4-methylpiperazin-1-ylmethyl) -N- [4-methyl-3- (4-pyridin-3-yl) pyrimidin-2-ylamino) phenyl] -benzamide or a pharmaceutically acceptable salt thereof Or 4-methyl-3-[[4- (3-pyridinyl) -2-pyrimidinyl] amino] -N- [5- (4-methyl-1H-imidazol-1-yl) -3- (trifluoromethyl ) Phenyl] benzamide or a pharmaceutically acceptable salt thereof. |