| abstract |
The present invention relates to binding molecules such as human monoclonal antibodies (human monoclonals), which contain H3 subtypes of HA, such as H3N2, and have broad neutralizing activity against such influenza viruses. This disclosure provides nucleic acid molecules encoding these antibodies, their sequences and compositions comprising the antibodies and methods for identifying or producing the antibodies. These antibodies can be used in the diagnosis, prevention and / or treatment of influenza virus H3N2 infection. In a preferred embodiment, these antibodies provide cross-subtype protection so that infection with H3, H7, and / or H10-flu subtypes can be prevented and / or treated. provide. |