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publicationDate 2012-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2012525883-A
titleOfInvention System, method, and luminescence marker for improved diffuse luminescence imaging or tomography of scattering media
abstract Disclosed are methods and systems for luminescent molecular imaging or tomography of a region of interest in a scattering medium. The system includes a non-linear luminescent marker material disposed in a scattering medium. Thereby, the contrast and resolution of imaging or tomography is improved. The non-linear marker is configured to up-convert incident light having an illumination wavelength, for example. The non-linear power dependence of the marker allows further improvement of imaging by using images obtained with two or more excitation beams at the same time.
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