| abstract |
The present invention acquires any one of a variety of desired properties including the degree of inhibition, maintenance of inhibition after cleavage of the serine protease inhibitor by the target serine protease, rate of binding to the serine protease, neutralization and binding affinity. Or relates to a method of modifying serine protease inhibitors to enhance. The invention also relates to the products of such modifications and the use of such products, particularly their use in therapy. [Selection figure] None |