| abstract |
The present application relates to 1,2,3,4,4a, 5,6,7-octahydropyrazino [1,2-a] [1,4] benzodiazepine of formula (I), 1,2,3,4 , 4a, 5,6,7-octahydropyrazino [1,2-a] [1,5] benzodiazepine, 2,3,4,4a, 5,6,7,11b-octahydro-1H-pyrido [3 , 4-d] [2] benzazepine, 1,2,3,4,4a, 5,6,7-octahydropyrazino [1,2-a] [1] benzazepine, 1,2,3,4, 4a, 5-Hexahydro-7H-pyrazino [1,2-a] [4,1] benzoxazepine and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino [2,1-d] [1,5] benzoxazepine and 5,6,7,7a, 8,9,10,11-octahydropyrazino [1 About 2-d] pyrido [3,2-b] [1,4] diazepine derivatives. Wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X 1 , X 2 , X 3 , X 4 , Y 1 , Y 2 and Y 3 are as defined in the specification. . The application also relates to compositions comprising such compounds, methods of treating disease states using such compounds and compositions, and methods for identifying such compounds. |