| abstract |
Disclosed are compositions for recovering, selecting, and transporting populations of nucleic acids from biological samples and clinical, forensic, or environmental samples. As a one-step formulation to kill pathogens, inactivate nucleases, and release polynucleotides from other cellular elements in the sample, and stabilize nucleic acids prior to further processing or assay Further disclosed is a method for using the composition. In certain embodiments, the present invention monitors the suitability of the recovery / transport medium and serves as an internal reference control for measuring the integrity of the nucleic acid that is subsequently isolated and purified from the treated sample, One, one-step, sample collection / transport / storage formulation containing a nucleic acid carrier molecule is provided. |