| abstract |
The present invention belongs to the field of the pharmaceutical industry and relates to a dosage form comprising a drug substance (API) such as tadalafil, simvastatin, fenofibrate and lovastatin adsorbed on a carrier and hardly soluble in water. Furthermore, the present invention relates to an adsorbate comprising an API that is hardly soluble in water, wherein the adsorbate is prepared using one (or more) nonpolar solvent such as chlorinated hydrocarbons, diisopropyl ether and hexane. Related to the method. Furthermore, the present invention relates to a method for preparing a dosage form, as well as the use of an adsorbate for preparing a dosage form. Furthermore, the present invention relates to a dosage form for use in the treatment of erectile dysfunction, human immunodeficiency virus (HIV) infection and / or acquired immunodeficiency syndrome (AIDS). |