| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2010-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2012-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012522508-A |
| titleOfInvention |
Differentially expressed microRNA as a biomarker for diagnosis and treatment of Sjogren's syndrome |
| abstract |
The identification of microRNAs that are differentially expressed in patients with Sjogren's syndrome is disclosed herein. By measuring the level of at least one differentially expressed miR gene product identified herein, a method of diagnosing a subject as having Sjogren's syndrome is provided. A change in the level of at least one miR gene product in the subject's biological sample relative to the control indicates that the subject has Sjogren's syndrome. By administering to a patient a therapeutically effective amount of an agent that inhibits the expression of a miR gene product that is up-regulated in patients with Sjogren's syndrome or compared to controls in patients with Sjogren's syndrome Also provided are methods of treating patients with Sjogren's syndrome by administering to a patient a therapeutically effective amount of an isolated miR gene product that is down-regulated. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591639-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018527915-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10822640-B2 |
| priorityDate |
2009-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |