http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012522233-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2010-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2012522233-A |
titleOfInvention | Fibrosis biomarker assay |
abstract | A method of diagnosing or quantifying fibrosis comprises performing an immunoassay that measures neoepitope-containing protein fragments that are naturally present in a sample of biological fluid, and increasing the measurement in the patient above normal levels. Associating with the presence or degree of fibrosis. The immunoassay comprises contacting a naturally occurring protein fragment in the sample with an immunological binding partner that is reactive against a neoepitope formed by cleavage of the protein by a proteinase; Measuring the degree of binding of the peptide fragment to the immunological binding partner to determine a protein fragment comprising: wherein the protein comprises type III collagen, type I collagen, It is type IV collagen, type V collagen or type VI collagen, elastin, biglycan, decorin, lumican, versican, perlecan, neurocan, brevican, fibrojuline, serglycine, syndecan, β-glycan, vimentin or C-reactive protein. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014522643-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019507731-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7091246-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017504040-A |
priorityDate | 2009-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 653.