| abstract |
The present invention relates to a compound of formula (I) (Wherein —R 1 is an —NR 5 R 6 group; unsubstituted or substituted phenyl; —R 2 is (C 1 -C 4 ) alkyl; —X—R 7 group; There; -R 3 and R 4 are each independently a phenyl substituted; is -R 5, a hydrogen atom or a (C 1 -C 4) alkyl; -R 6 is unsubstituted, Or substituted (C 1 -C 4 ) alkyl;-or R 5 and R 6 together with the nitrogen atom to which they are attached, an unsubstituted or substituted heterocycle —X is (C 1 -C 5 ) alkylene; —R 7 is —OR 8 group, —NR 9 R 10 group or —SO 2 — (C 1 -C 4 ) alkyl group in it; -R 8 is a hydrogen atom or a (C 1 -C 4) alkyl; -R 9 are It is hydrogen atom or a (C 1 -C 4) alkyl; -R 10 represents a hydrogen atom, -COR 11 group, be -SO 2 R 11 group or -CO (CH 2) m OH groups; -R 11 is , Unsubstituted or substituted (C 1 -C 4 ) alkyl; -m is 1, 2 or 3.). The invention also relates to a process for the preparation of compounds of formula (I) and to their therapeutic use. |