| abstract |
The invention described herein relates to novel fused pyrimidinedione derivatives of formula (I) that are TRPA (transient receptor potential subfamily A) modulators. In particular, the compounds described herein are useful for the treatment or prevention of diseases, symptoms and / or disorders that are modulated by TRPA1 (transient receptor potential subfamily A, member 1). The invention also treats or prevents the compounds described herein, intermediates used in their synthesis, methods of preparing pharmaceutical compositions thereof, and diseases, symptoms, and / or disorders modulated by TRPA1. Provide a way to do it. [Selection figure] None |