http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012520902-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 |
| filingDate | 2010-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012520902-A |
| titleOfInvention | Method of modifying hyaluronic acid with (O-acyl-O'-alkyl carbonate-substituted pyridine) complexes |
| abstract | The present invention provides a novel preparation of hyaluronic acid derivatives by reaction of hyaluronic acid with complexes of the general formulas R—CO—O—CO—O—R1 and R25C5N (O-acyl-O′-alkyl carbonate-substituted pyridines) Regarding the method. The reaction takes place in DMSO in the presence of an external base and an O-acylated product is formed. In this method, the degree of substitution is high and the reaction time is short compared to known similar methods, and when the drug contains two or more functional groups R (CO-O-CO-O-R1) n, the crosslinked hyaluronic acid A derivative is formed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016500130-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017519785-A |
| priorityDate | 2009-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.