| abstract |
The present invention relates to compounds of general formula (I) In the formula: R is independent of a hydrogen atom or a halogen atom and a (C 3 -C 7 ) cycloalkyl group, a (C 1 -C 6 ) alkyl group, a (C 1 -C 6 ) alkoxy group, and a hydroxy group. optionally substituted by one or more groups selected Te (C 1 -C 6) alkyl or (C 3 -C 7) - is a radical selected from cycloalkyl group; R 1 is a halogen atom And (C 1 -C 6 ) alkyl group, (C 1 -C 6 ) alkoxy group, halo (C 1 -C 6 ) alkyl group, hydroxy group, halo (C 1 -C 6 ) alkoxy group, (C 1- Optionally substituted by one or more substituents independently selected from C 6 ) alkyl-thio groups, (C 1 -C 6 ) alkyl-SO groups, and (C 1 -C 6 ) alkyl-SO 2 groups. Phenyl group There; R 2 is a hydrogen atom, a halogen atom, and halo (C 1 -C 6) alkyl group, (C 1 -C 6) alkyl group, (C 3 -C 7) cycloalkyl, (C 3 -C 7) - cycloalkyl - (C 1 -C 3) alkyl group, a phenyl group, a benzyl group, (C 1 -C 6) alkoxy groups, (C 1 -C 6) alkyl - thio, (C 1 -C 6 ) alkyl -SO group, and (C 1 -C 6) be one or more substituents selected from alkyl -SO 2 group; Het is a heteroaryl group; the compound, base or acid addition salt It is a form. The invention also relates to this therapeutic use and this synthetic method. |