http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012519694-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2010-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012519694-A |
| titleOfInvention | Pharmaceutical compositions for ocular delivery of receptor tyrosine kinase inhibitor (RTKi) compounds |
| abstract | The present invention relates to the development of an effective pharmaceutical composition in the form of an aqueous solution comprising an active agent in a therapeutically effective amount and polyethylene glycol having a molecular weight of at least 2000. In another embodiment, (a) an active agent (eg, an anti-angiogenic compound, anti-inflammatory compound, or anti-vascular permeability agent); (b) an appropriate amount of high molecular weight PEG; (c) an appropriate buffer; Provided is a post-sclera (PJ) and periocular (PO) formulation comprising (d) an isotonic agent as required; and (e) a surfactant. The solutions described herein are preferably substantially free of ionic species. |
| priorityDate | 2009-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.