| abstract |
The present invention relates to compounds having the structural formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. This compound has cardiovascular disease, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina, thrombosis, restenosis, myocardial infarction, stroke, heart failure, pulmonary muscle tone It is useful for the treatment or prevention of hypersensitivity, erectile dysfunction, bronchial asthma, chronic renal dysfunction, diabetes and cirrhosis. [Chemical 1] |