http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012512862-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-135 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 |
| filingDate | 2009-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012512862-A |
| titleOfInvention | Preparation process of piperazine derivatives |
| abstract | The present invention involves reacting a compound of formula (III) with a carbamoyl chloride of formula (II) to produce trans-N- {4- {2- [4- (2,3-dichlorophenyl) -piperazine- The invention relates to a process for preparing 1-yl] -ethyl} -cyclohexyl} -carbamide derivatives, which are reacted in a mixture of a solvent and a concentrated aqueous alkali hydroxide solution at a temperature of 40-100 ° C. in the presence of a phase transfer catalyst. , Separating the phases, washing the organic layer and then removing the solvent, drying the compound of formula (I) obtained until the weight is constant. |
| priorityDate | 2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 13.