http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012511896-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-10034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-10032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2009-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2012511896-A |
titleOfInvention | PCV2-based methods and compositions for pig treatment |
abstract | The present invention relates to methods and compositions for vaccinating pigs against porcine circovirus type 2 (PCV2) related diseases. In particular, the present invention relates to recombinant expression vectors that allow for secretion or cell membrane expression of truncated forms of PCV2 open reading frame 2 (ORF2) protein. In particular, the present invention relates to a recombinant expression vector comprising a nucleic acid sequence encoding a modified PCV2 ORF2 operably linked to a promoter, wherein the modified PCV2 ORF2 removes the nuclear localization signal of the wild type PCV2 ORF2. Or has been modified to allow secretion of a truncated ORF2 protein upon expression; or the modified PCV2 ORF2 is a cell in which the nuclear localization signal has been removed and the infected cell Replaced with a hydrophobic signal sequence directed to the expression of the PCV2 ORF2 on the surface. |
priorityDate | 2008-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 944.