| abstract |
The present invention provides a peptide vector of formula AXB, wherein A is a peptide vector that can cross the blood brain barrier or facilitate the transport of a compound into a specific cell type, X is a linker, and B is leptin, It is a leptin analog or an OB receptor agonist]. The compounds of the present invention can be used to treat diseases where an increased amount of leptin is desired, for example metabolic diseases including obesity and diabetes. [Selection] Figures 1A and 1B |