| abstract |
Disclosed are human serum albumin (HSA) linkers and HSA linkers coupled with binding agents, diagnostic agents, and therapeutic agents. Also disclosed are conjugates in which the HSA linker and the first and second single chain Fv molecules (scFv), the amino-terminal and carboxy-terminal binding moieties, are covalently linked. Exemplary conjugates are useful for reducing tumor cell growth, eg, for therapeutic uses. Also disclosed are methods and kits for diagnostic and therapeutic uses of HSA linker conjugates. |