| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2009-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2012-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012507985-A |
| titleOfInvention |
Improved method for isolating enveloped virus-based VLPs free of infectious agents |
| abstract |
An enveloped virus-based virus-like particle (VLP) is described that is free of infectious agents and is substantially as immunogenic as the corresponding VLP prior to inactivating the infectious agent. An improved method for inactivating infectious agents in enveloped virus-based VLP preparations that does not deleteriously affect the immunogenicity of VLPs is also described. The method comprises the steps of: (a) isolating an enveloped virus-based virus-like particle preparation from a host cell or a component of the host cell used to make the enveloped virus-based virus-like particle preparation; b) applying to the preparation a dose of electromagnetic radiation sufficient to inactivate substantially all infectious agents in the enveloped virus-based virus-like particle preparation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015004997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015015931-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10792353-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019500907-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7150611-B2 |
| priorityDate |
2008-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |