Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate |
2009-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2012507486-A |
titleOfInvention |
Radiolabeled inhibitor of glycine 1 transporter |
abstract |
The present invention relates to a novel radiolabeled inhibitor of general formula (I) for glycine 1 transporter (GlyT1) useful for labeling and imaging of glycine 1 transporter functionality. Where R 1 is isopropoxy or 2,2,2-trifluoro-1-methyl-ethoxy; and R 2 is a radiolabeling group: CH 3 (wherein the radionuclide is 3 H or 11 C). It has been found that the radiolabeled compound of formula (I) can be used as a radioactive tracer in PET (Positron Emission Tomography) for glycine 1 transporter functional labeling and molecular imaging diagnostics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011158323-A |
priorityDate |
2008-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |