abstract |
Compounds of formula (I) useful as antagonists of CGRP receptors and useful for the treatment or prevention of diseases involving CGRP receptors such as migraine, in particular migraine and cluster headache, wherein Element A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , J, Q, R 4 , E a , E b , E c , R 6 , R 7 , R e , R f , R PG , Y and Z are as described herein). The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases involving CGRP receptors. |