http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012503648-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 2009-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012503648-A |
| titleOfInvention | Method for producing montelukast sodium salt |
| abstract | The manufacturing method of the montelukast sodium salt represented by Formula (1) is disclosed. In this method, in the presence of an alkali metal salt of bistrimethylsilylamide, a methanesulfonyl compound represented by the following formula (2) is coupled with a compound represented by the following formula (3), an alkali metal base is further added thereto, and the mixture Is heated to prepare a compound represented by the following formula (4), and the compound represented by the formula (4) is reacted with 4-tert-butylcyclohexylamine and then purified to obtain the formula (5 And a step of converting the amine salt represented by the formula (5) into a sodium salt. [Selection] Figure 1 |
| priorityDate | 2008-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.