| abstract |
Compounds that are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo [1,2-a] pyrazin-1-one compounds, or pharmaceutically acceptable salts thereof, methods for their preparation and A pharmaceutical composition comprising these is disclosed. These compounds may be caused by and / or associated with alterations in protein kinase activity such as cancer, viral infection, prevention of AIDS in individuals infected with HIV, cell proliferation disorders, autoimmunity and neurodegenerative disorders. Useful for treatment. Also disclosed are methods of preparing the compounds of the invention under solid phase synthesis conditions and chemical libraries comprising a plurality of these compounds. |