http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012502939-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 |
| filingDate | 2009-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2012502939-A |
| titleOfInvention | Purification of erythropoietin |
| abstract | In the present invention, a method for purifying erythropoietin comprising at least one chromatography step using a stationary phase containing hydroxyapatite is reported. This method comprises the following steps: i) Erythropoietin in a solution containing calcium ions is equilibrated with a solution containing calcium ions, ie under conditions where erythropoietin binds to a stationary phase containing hydroxyapatite. Ii) passing a solution containing less calcium ions than the previous solution through a stationary phase containing hydroxyapatite derived from i), in which case erythropoietin is immobilized with hydroxyapatite. And iii) pass further solution containing calcium ions below 0.5 mM through the hydroxyapatite-containing stationary phase from ii), thereby separating erythropoietin from the hydroxyapatite-containing stationary phase. ,including. |
| priorityDate | 2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 529.