http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012244925-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbfdc7316d3b1b7ceaee5366a61b6e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe9efcec7d9ed77f844ba87d886fb92c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a84cb002b2ec695e5aa5125b0649294 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_100ddb6b6a76ed43742f8a6ef8acadfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d58e6b4439cc92917150168b79337b0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eb0e688eb114aee830ba8ed1a0d28e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f86a14e399cf475158558b8103c0d3a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a898521db74b8d2660e817ea647af48 |
publicationDate | 2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2012244925-A |
titleOfInvention | GENE TRANSFER AGENT COMPOSITION AND METHOD FOR PRODUCING THE SAME |
abstract | The present invention relates to a non-viral vector that has excellent gene transfer activity and can be transferred to stem cells and primary cells (primary cells: cells that have just been separated from a living tissue) that have been difficult to transfer with conventional non-viral vectors. A gene transfer agent composition is provided. One or more selected from the group consisting of 2-N, N-dimethylaminoethyl methacrylamide, 2-N, N-dimethylaminoethyl methacrylate and 3-N, N-dimethylaminopropyl acrylamide. A gene transfer agent composition comprising a complex comprising a nitrogen-containing polymer containing a structural unit derived from a nitrogen-containing monomer and a nucleic acid, and a cell disruption product. Gene transfer agent composition can be dramatically improved by mixing cell disrupted material with a complex of nitrogen-containing polymer and nucleic acid, thereby enabling gene transfer to stem cells and primary cells. Become. [Selection] Figure 1 |
priorityDate | 2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 485.