| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d42f684941d5b0617ca7764ebdff07 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16651
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
| filingDate |
2012-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f61b14737c8a76226442661e2dcff340
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f0a4000b43394f4bb244d46e18968fb |
| publicationDate |
2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012235788-A |
| titleOfInvention |
Method for producing a recombinant AAV virion preparation substantially free of empty capsids |
| abstract |
The present invention provides a novel method for enhancing production capacity by removing empty capsids from AAV vector particle stock or reducing the number of empty capsids. Empty capsids can be separated from rAAV virions containing genetic material ("AAV vector particles") by using column chromatography techniques. A method for separating an AAV empty capsid from a mixture of AAV vector particles and an AAV empty capsid. This method uses column chromatography techniques to produce commercially viable levels of recombinant AAV virions. [Selection figure] None |
| priorityDate |
2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |