| abstract |
Disclosed is a pharmaceutical composition for use in either or both of at least partially ameliorating or at least partially inhibiting mammalian dermatitis. Compositions and methods for directing and / or suppressing inflammation, for example by inhibiting prostaglandin and / or COX-2 production, which comprises at least one indole quinazoline alkaloid (preferably Is used in combination with butyleneated hydroxytoluene). Preferred indolequinazoline alkaloids are lutecarpine, evodiamine, and dehydroevodiamine, which are found in nature in an unpurified form in the Chinese medicine Wu-Chu-Yu consisting of the herb, evodiartecarpa. [Selection] Figure 1 |