| abstract |
Provided is a vesicle composition having excellent stability against pH change and storage stability. The following components (A), (B) and (C): (A) General formula (1) [Wherein R 1 represents a natural sterin having one hydroxyl group or a hydrogenated product thereof, or a residue remaining after removing a hydrogen atom of a hydroxyl group of bile acid, and R 2 represents a carbon number of 1 to 24 M represents a hydrogen atom, an alkali metal, an alkaline earth metal, ammonium, an alkanol ammonium having 2 to 9 carbon atoms, an alkyl ammonium or alkenyl ammonium having 1 to 22 carbon atoms, carbon Represents a pyridinium substituted with an alkyl group or an alkenyl group of 1 to 18 or a basic amino acid], 0.0001 to 20% by mass of an organic acid represented by (B) 0.0001 to 10% by mass of sphingosines, (C) A vesicle composition containing water and having a pH of 2 to 11. [Selection figure] None |