abstract |
The present invention provides a hedgehog signal inhibitor or the like containing a fused-ring heterocyclic derivative or a pharmaceutically acceptable salt thereof as an active ingredient. The following general formula (I) [In Formula (I), R 1 represents a hydrogen atom, R 2 represents a hydrogen atom, R 3 represents a lower alkyl which may have a substituent, and A represents a substituted group. A cycloalkyl optionally having a group, etc., and B is a 5- or 6-membered non-aromatic ring optionally having a substituent, together with -C = C- of the adjacent pyrrole ring L 1 represents a formula (i) or the like, L 2 represents a formula (iii) (wherein R 4 represents a hydrogen atom or the like), a formula (iv), or the like, and L 2 Is a formula (iv) or the like, Q is not present, and when L 2 is a formula (iii), Q is absent or represents an oxygen atom] Provided is a hedgehog signal inhibitor containing a pharmaceutically acceptable salt as an active ingredient. [Selection figure] None |