| abstract |
A method of administering pirfenidone to a patient who has shown abnormalities in biomarkers of liver function in response to pirfenidone administration. The method includes the steps of administering to a patient a dose of pirfenidone that is less than a full target dose for a period of time, followed by a full target dose of pirfenidone. The method also includes administering a full target dose of pirfenidone without reduction and administering a consistently reduced dose of pirfenidone. [Selection figure] None |