http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012175955-A

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filingDate 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5115ce5594db6f1433c63c7d93722612
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publicationDate 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2012175955-A
titleOfInvention Novel substance having activity enhancing action of antifungal agent, production method and use thereof
abstract The present invention provides a novel compound having an activity-enhancing action of antifungal agents such as polyene macrolides and azoles and a method for producing the same. A polyene macrolide drug and an azole drug are produced by culturing Simplicilium sp. FKI-4981, which is a microorganism having the ability to produce FKI-4981B substance represented by the following formula [I]. Because it has an activity enhancing action of antifungal agents such as, it is effective at low concentrations and in a short period of time for many fungal infections including deep mycosis, and is useful for reducing the frequency of appearance of resistant bacteria. It is a compound that is expected to be useful for overcoming resistance. [Selection figure] None
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