abstract |
The present invention provides an enamel regeneration solution and an enamel regeneration kit that cause enamel remineralization in vivo and are useful for treating initial caries and preventing caries. An enamel regeneration solution contains amelogenin, calcium ions, and phosphate ions. The enamel regeneration kit includes a first solution containing calcium ions and a second solution containing amelogenin and phosphate ions. Amelogenin accumulates on the surface of the enamel to form a space. In this space, calcium ions and phosphate ions accumulate, and the local supersaturation promotes the reaction between calcium ions and phosphate ions, thereby producing hydroxyapatite crystals. grow up. [Selection] Figure 12 |