Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ab3e1d2b9a4794709fe79651849d76e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_267d482a3667501fdc81115774c324f8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-44 |
filingDate |
2011-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8935c523e7d0bdcc4e4f3f83af402e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_949c8014d00fbf5bab1b096e45952c87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bec55c992d6ae93a7261984d0c2da25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fda161dad5f4c5db0f476ff2f0160e52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da24da0f4e8f53f6ea8ff290d832cade http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e7697547b7a935ea253a7d848fbe94c |
publicationDate |
2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2012158524-A |
titleOfInvention |
NOVEL CARBA SUGAR PRECURSORS, PROCESS FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING BIOLOGICALLY ACTIVE CARBUCAGASA AMINE DERIVATIVE USING THEM |
abstract |
Kind Code: A1 The present invention relates to a novel method for producing a physiologically active carbsaccharide amine derivative useful as a therapeutic agent for lysosomal disease, a novel carbasugar precursor useful as a production intermediate in the production of the above carbsaccharide amine derivative, and a method for producing the same. provide. The following general formula (1) [Chemical 1] [Wherein, part or all of R 2 to R 4 each independently represent a hydrogen atom or a hydroxyl-protecting group. R 1 and R 5 represent an acyl group having 2 to 15 carbon atoms. A novel carbasugar precursor characterized by having an absolute configuration represented by the following formula, and subjecting the precursor to Wittig reaction conditions, halogen addition to the resulting diene, followed by substitution reaction to produce an acyloxyl group Then, an alkylamino group can be introduced to obtain a physiologically active carbacylamine derivative. [Selection figure] None |
priorityDate |
2011-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |