abstract |
The present invention provides a novel compound, a pharmaceutical composition, and a method for inducing dedifferentiation for inducing dedifferentiation of mammalian cells into multipotent stem cells. A compound of the formula I (wherein R 1 is a 3-chlorophenyl group, 4-dimethylaminophenyl group, 2-pyridyl group, 6-quinonyl group, etc., R 2 is a cyclohexylmethylamino group, cyclohexylamino A group, a phenylsulfonyl group, etc.), a pharmaceutical composition containing the compound, and contacting an isolated lineaged mammalian cell with the compound to dedifferentiate the mammalian cell into a multipotent stem cell A method for inducing dedifferentiation of lineage-determined cells, comprising: [Selection figure] None |