abstract |
The present invention provides structure-based methods and compositions useful in designing, identifying, and producing molecules that act as functional modulators of TDF-like receptors. Tissue differentiation factor-related polypeptide (TDFRP) compounds having specific amino acid sequences, as well as variants, analogs, homologues, or fragments of these polypeptides, and small molecules associated therewith. A pharmaceutical composition having a TDFRP compound with or without a pharmaceutically acceptable carrier. A method of treating or preventing a tissue differentiation factor-related disorder. [Selection figure] None |