| abstract |
A biosensor for detecting the presence of a target analyte is provided. A binding partner for a target analyte is formed from microspheroid particles and immobilized on its surface, the binding partner being a nucleotide; a peptide, a protein, an enzyme, an antibody, etc. When bound to a partner, the whispering gallery mode (WGM) profile of the micro-spheroid particles changes so that the profile peak shifts red or blue, and the immobilized binding partner makes them fluorescent, phosphorescent, incandescent Such as fluorophores, such that they can take the form of nanocrystals or quantum dots. [Selection figure] None |