| abstract |
Methods of treating disease states associated with angiogenesis and / or increased vascular permeability, and agents for use in producing anti-angiogenic and / or vascular permeability reducing effects in warm-blooded animals such as humans , Pharmaceutical compositions, and methods of their use. A quinazoline derivative represented by the following general formula (I) and a pharmaceutical composition containing them. [Wherein ring A is a phenyl ring or a 5- or 6-membered heterocyclic ring as defined herein; Z is —O—, —NH— or —S—; m is an integer from 0 to 5. ] [Selection figure] None |