http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012125256-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43e3d3af182596070faf38852f7c7c4f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9894ad5db16d7b88e5ec10d10f1c3a5 |
publicationDate | 2012-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2012125256-A |
titleOfInvention | Production of birds and other animals resistant to viral diseases |
abstract | A germ cell encoding a siRNA targeting a viral sequence and a method for obtaining the germ cell are provided. The present invention relates to genetically modified animals that are resistant to viral infection. Also provided is a method of making an animal that is resistant to viral infection. According to the invention, a non-human vertebrate germ cell comprising a construct comprising a siRNA encoding sequence for a conserved region of the viral genome, wherein the sequence is operably linked to a promoter. Germ cells are provided. The present invention also provides a non-human vertebrate that is resistant to viral disease, wherein the majority of cells in the vertebrate are conserved in the genome of the virus responsible for the disease. Also provided is a non-human vertebrate comprising a sequence encoding siRNA for the region, said sequence operably linked to a promoter. [Selection figure] None |
priorityDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 396.