| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-20222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-766
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate |
2010-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8e32c62e99684e138121d62fe552b0e |
| publicationDate |
2012-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2012110290-A |
| titleOfInvention |
Neuron-specific retrograde transport vector |
| abstract |
To provide a lentiviral vector system that retains a high frequency retrograde transport ability in an animal brain and has a higher titer. (1) A packaging plasmid containing HIV-1 gag and pol genes; (2) a packaging plasmid containing an accessory gene for HIV-1; (3) a transfer plasmid containing the gene of interest; and (4) as envelope genes, the N-terminal region of the extracellular domain of the rabies virus glycoprotein (RV-G) and the vesicular stomatitis virus glycoprotein (VSV-G). An envelope plasmid comprising a gene encoding a fusion extracellular domain comprising the C-terminal region of the extracellular domain, a transmembrane domain of RV-G or VSV-G, and a fusion polypeptide comprising the intracellular domain of VSV-G, A kit for preparing a retrograde transportable virus vector. [Selection] Figure 2 |
| priorityDate |
2010-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |