| abstract |
A novel 9-substituted minocycline compound is provided. A novel 9-substituted minocycline compound is represented by the following formula, for example. The site of naphthylthiourea can be various substituents such as phenylurea and phenylsulfonic acid amide. These minocycline compounds are commonly used to treat many tetracycline compound-responsive states such as bacterial infections and neoplastic diseases, as well as general minocycline, such as inhibiting tetracycline excretion and modulating gene expression. And can be used for other known applications of tetracycline compounds. [Selection figure] None |