abstract |
Disclosed is a compound useful as an active ingredient of a pharmaceutical composition for treating a disease involving 17βHSD type 5. [MEANS FOR SOLVING PROBLEMS] The present inventors have investigated therapeutic agents for diseases involving 17βHSD type 5, and confirmed that amide compounds having a hydroxyalkyl group on a cyclic amino group have potent 17βHSD type 5 inhibitory activity. The present invention has been completed. The amide compound of the present invention can be used as an active ingredient of a pharmaceutical composition for preventing and / or treating diseases involving 17βHSD type 5 such as prostatic hypertrophy and prostate cancer. [Selection figure] None |